Brain fingerprints of structural connectivity in health and disease

Tim van Hartevelt (Oxford U, UK) replacing Henrique Fernandes (U Aarhus, Denmark)

Brain structure and function are closely related and can influence each other. Brain structure can influence the flow of information through the network. The network dynamics can in turn shape and reshape structure over time. In order to optimally use many computational models, we often need an accurate structural connectome as the backbone and input to such models.
As brain dynamics can be highly informative, the underlying structure can sometimes be overlooked. There is a wealth of information available in structural networks and they can reveal crucial information about patient groups. The structure and connectome can be used to plan for neurosurgery including the implantation of deep brain stimulation electrodes in the right location.
Here I will show how structural connectivity can be used in healthy groups as well as patient groups. Furthermore I will show to what extend structural connectivity and whole-brain dynamics are related to and influenced by each other using diffusion tensor imaging, resting-state functional MRI and computational modelling together.